Rat Anti-Mouse F4/80 mAb (AF488)

簡(jiǎn)要描述：Rat Anti-Mouse F4/80 mAb (AF488)

產(chǎn)品型號(hào)：781021
廠商性質(zhì)：生產(chǎn)廠家
更新時(shí)間：2025-08-21
訪問量：159

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產(chǎn)品介紹：

產(chǎn)品詳情

同源性比對(duì)：

Q61549

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稀釋比

FC-5μL per test for million cells or whole blood in 100 μL volume.

SwissProt ID

Q61549

宿主

Rat

偶聯(lián)物

AF488. Ex:490nm.Em:525nm.

修飾

Unmodified

基因 ID

13733

基因名

Mouse F4/80

亞型

IgG2b

克隆性

Monoclonal Antibody

克隆號(hào)

CI:A3-1

免疫原

A synthesized peptide derived from Mouse F4/80

研究領(lǐng)域

Immunology

背景信息

F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.

純化方式

Affinity Purified

形式

Liquid

存儲(chǔ)緩沖液

Liquid in PBS with 0.05% Proclin300, 1% BSA

保存溫度

Store at 2-8°C..Avoid light.Avoid freeze/thaw cycles.